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About Us

About Us

Missouri Breaks Industries Research Inc. (MBIRI) is a small Indian-owned business. Our main office is located on the Cheyenne River Sioux Reservation in South Dakota, and we have satellite offices on the Oglala Sioux Reservation (SD), Spirit Lake Nation (ND), and in Rapid City, SD. MBIRI is qualified under 25 USC 47 as a “Buy Indian” business to conduct research of medical problems and to disseminate information learned through this research to health care providers, tribal leaders, and community members.




Our company logo and name, Missouri Breaks, are inspired by the Missouri River. The river is the life-blood of our entire region. The breaks of the river are where Lakota people historically found water, wood, wild game, plant medicines, and protection. To us, the breaks of the Missouri River represent abundance. All of our work strives to regain abundance in the communities we serve.

Missouri Breaks Logo with Name Tagline (Creating Opportunities for Health)  and Mission (Advancing Innovative Solutions Through Partnerships, Data & Understanding).
Image of Missouri Breaks employee doing paperwork.
Missouri Breaks employee interacting with a participant in a clinical exam room.


1982 - Tim and Marcia O’Leary founded Missouri Breaks Industries Research Inc. to promote American Indian made products throughout the Dakotas

1990 - Marcia began working as the Strong Heart Study nurse on the Cheyenne River, Oglala, and Spirit Lake Nations

1995 - Became a legal entity and reorganized to become an Indian-owned research company that oversaw the Dakota Center for the Strong Heart Study 

2000 - Opened a research office on the Pine Ridge Reservation

2004 - Expanded scope to include delivery of medical equipment

2007 - Incorporated public health projects

2011 - Opened a medical equipment office in Martin, SD to serve the Pine Ridge and Rosebud Reservations

2018 - Opened a research office in Rapid City, SD


Missouri Breaks is a family business that employs around 50 people throughout western South Dakota. Over 80% of our employees are enrolled tribal members and all are long-time members of the communities that they serve.

Community Advisory Board (CAB) Members: The purpose of the CAB is to ensure our research fits the Community-Based Participatory Research (CBPR) model. The scope of the CAB is to provide input on current research projects, future research projects, and their view on the health issues of our tribal communities. The CAB also assists in dissemination of research outcomes, evaluating research processes and tools, and advocating for the importance of health research. If you are a community member of the Cheyenne River or Oglala Nations and are interested in becoming a CAG member, please email

Missouri Breaks employee interacting with participants in a conference room.
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