Factors Influencing Pediatric Asthma (FIPA)

Specific Aim 1) Characterize the influence of risk factors and the resulting disability of asthma in the Cheyenne River Sioux and Oglala Sioux communities utilizing a case/control methodology. Specific Aim 2) Test the hypothesis that intensive patient education regarding self-directed, stepped care will result in reduced morbidity and medical care utilization, while increasing quality of life. Specific Aim 3) Explore and test various hypotheses regarding associations between certain genetic polymorphisms and risk of asthma or response to medication. Specific Aim 4) improving the understanding of research methods and encouraging young American Indian students to consider careers in biomedical fields.

Study Documents:

All items containing study results have undergone review and approval from the participating Tribe and Great Plains IRB.

• Project Summary

• Parental Consent Form for Study

• Parental Consent Form for Breathe Intervention

• Minor Assent Form for Study

• Minor Assent Form for Breathe Intervention

• Participant Results Newsletter

• RED Talk Video on Initial FIPA Results

• Publication on Immune Factors of Asthma by Best et al. (2016)

• Publication on Genetic Variants of Asthma by Best et al. (2017)

• Poster Presentation on Social Determinants of Asthma by Kinghorn et al. (2019)

• Publication on Social, Economic, and Environmental Risk Factors of Asthma by Kinghorn et al. (2019)

• Publication on the BREATHE Asthma Intervention by O'Leary et al. (2022)

• Final CRCAIH Report

We are excited to share that as of 2022, the study team began a follow-up study called Factors Influencing Pediatric Asthma into Adulthood (FIPA2).